Top definition
To puope is to poop and puke at the same time. Usually the poop is runny, like diarrhea.
Roxanne: Ugh, I had the worst night ever last night.

Tonya: Did you puope again?

Roxanne: Yes ):
by toofat2live October 22, 2010
Get the mug
Get a Puope mug for your mother-in-law Yasemin.