POO- shAH! Not sure if the spelling, but Is a cajun exclamation that means ‘that can’t be possible’ or calling bullshit on something. I like to think it means ‘poor dear’ or potentially po - cher. Can’t believe you would really believe that...definitely can’t believe you would think I would buy it!
Your friend: Green snakes turn blue when they die.
You: Poosha! Ter ain’ no way!
A Pooshee is neither an insult or a compliment. But it can also be both, or one of the two. It depends what the person saying the word has for an intent.