Top definition
must be prounounced "pi-LOW-pis" (to disguise in public), it's the geniously crafted marriage of Pillow and Pussy... As seen in the majority of 40+ year old women who've borne children, and subsequently grown that strange bulge between the nether region and the belt.
Bill: Dude, your mom looks pretty hot, but what's the deal with the pillopus?

Ted: Dude, not cool.
by BeerImmediately March 15, 2009
Get the mug
Get a Pillopus mug for your father-in-law Jerry.