Perma-Fucked 

The state of being permanently altering your future or your body negatively, due to injury or a retarded decision.

I cut the nerves and tendons in my finger and now it's perma-fucked. I knocked a random girl up after a one night stand and now I'm Perma-fucked

Perma-Fucked by Bonnie's hubby May 4, 2017

perma fucked 

The state of being that resulted from long periods of drinking excessively.

LB tried to answer the cop's question but he was so perma fucked he couldn't even understand him.

perma fucked by d bo April 22, 2004

Perma Fucked 

(aka Chloe Ritter) when your brain has

Deteriorated Too the point of no return from the excessive use of methamphetamines. Akaa The boofaaLoompa of Bristol

That tweaker is perma fucked !

Perma Fucked by forbiddinknowlage July 13, 2021

Permafucked 

Being permanently Fucked.

"Yea, I've just been permafucked... my car's gone..."

Permafucked by Eric Zabowski February 2, 2009