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As seen in medical jargon... PRN abbreviates the Latin "Pro Re Nata" which translates to "as matters stand."
Nurses have told me more than once, it means "Patient Report Need" which would seem to be technically incorrect, but is much closer to the functional meaning. (1st Example)

When seen in a prescription, it means "as needed"... the same as "patient reports need" but with no further requirement to report to or consult with the doctor." (2nd Example)
"As Patient reports no further pain or weakness at left knee, no additional followup is scheduled. Patient was instructed to return to the clinic PRN."

"Take two tablets three times a day PRN for pain."
PRN by AppleJohn March 2, 2015
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Medical shorthand terminology for whenever necessary (pro re nata)which basically means its an excuse for the staff to be driven crazy prn.
"what the patient in 1408 really needs is a bath prn..god!"

"what smart jerk wrote the order for a hand job prn???"
PRN by DaynaS February 17, 2008
Related Words
when you try to spell porn too fast and miss the o.
Person 1: *types prn*
Person 2: Hahaha, you spelled porn wrong!
prn by mastoid45 March 31, 2019
A term for porn, when porn is banned in a chat
I watched prn = I watched porn
simple abbreviation that means pooping right now popularized from usian poop. the fastest shitter in thne world of war craft
Mom I can't take grandpa out for a walk I am PRN
PRN by anonymous April 12, 2024

PRN (Punk Rock Nigger) 

We all know you have these in your town. The 'odd one out'. A black human being who is demonstrating their 'uniqueness' by shopping at Hot Topic, galavanting around with the white kids who have mohawks.

they come complete with spikes on their jacket, lace-up stomp boots, and custom made band shirts. The classical black kid makes fun of these PRNS. You kinda feel bad. But then you laugh.

I guess you could say these sex pistols-loving niggas march to the beat of a differant drum. (A non triabl african one, of course.)
"Yo, Hannah and Jackie--LOOK AT THAT PRN (Punk Rock Nigger)! IM MORE BLACK THAN HIM!"

"Yeah, so my son is a PRN (Punk Rock Nigger). I dont know where i went wrong, Latisha."
PRN (Punk Rock Nigger) by K-Dawg . January 2, 2006

PRN princess 

A person (most commonly a female nurse) who works PRN because they do not need full-time benefits at their place of employment. They are usually supported financially by a spouse, their parents, or a savings account which allow them to do so. Majority of them have full-time commitment issues.
“Why was Becca not scheduled to work on Christmas Eve?”
Oh, that’s because she’s a PRN princess”
PRN princess by endonurse1825 April 28, 2024