Just generally trippin', tweakin', weird, actin' a fool, blackin' out, goin' off. Not necessarily due to drugs, though that's the obvious reference.
Homie was on one, just buggin' like I shot his mom or something.
by Kuahmel January 23, 2009
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1. When you go from dating someone to being in an exclusive relationship.
2. Becoming someone's boyfriend or girlfriend.
Friend 1: Dude, when are you guys gonna go one on one?
Friend 2: I'm not ready for a relationship yet.

Friend 1: I thought you were going one on one with her.
Friend 2: Naw, man. I don't want to give up the other pussy.
by Juppy George January 16, 2009
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while playing basketball, if you get fouled on a shot AND make it....
"he takes it strong to the hole...(gets fouled and make da layup)AND ONE BABY!"
by tara January 5, 2004
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absolutely, positvely the only person on earth you are meant to be with. soul mate and best friend.
by Kate June 22, 2003
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A redundant way for uneducated people to say "these."
Your friend: "Do you like these ones?"
You: "Yeah, _these_ are nice."
by jcwla December 27, 2007
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the person you spend your whole life looking for.
I have finally found the one.
by Peter Donohoe June 28, 2003
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