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Means to have to defecate or have a bowel movement or to have to take a dump. Mainly used for an emergency situation, where the movement in imminent, but can be used for any announcement of your condition.
Remember that jalepeno burrito I had earlier, with the ice cream sundae and Heinekins for dessert? Well, Mr Hankey is knocking on the door about now!!

I've been sick all day, and I think Mr Hankey is knocking on the door again.
by PALABRAMAN July 17, 2009
mugGet the Mr Hankey is Knocking on the Doormug.

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