A negative term used to refer to Mark Zuckerberg, founder and CEO of Facebook.
Mother Zucker changed Facebook's layout again. It was probably just a distraction to keep us from noticing the horrible privacy settings.
by Roger Nadsworth October 6, 2010
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A way to swear at someone while also blessing them at the same time. Instead of Mother F'er, this is the more appropriate "Mother Zucker".

swearing b/c it has the same force and intent of the F word -- but a blessing b/c Mark Zuckerberg has become a billionaire and one of the most influential people of our time (whether or not people like him).
As in - "you Mother Zucker -- i can't believe you got ANOTHER promotion"

As in - "all these mother ZUCKERs need to go ZUCK themselves"
by eSoulbb December 5, 2011
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