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Mason-Dixon line 

Anywhere that defines a specific boundary, especially regarding someone's body or personal space.
"Keep your hands above the Mason-Dixon line, thanks."
Mason-Dixon line by TheMocker December 30, 2013

Mason-Dixon Line 

A latitude line in the United States which divides Idiots and Assholes
Goddamnit Johnathan! How can I get away from all these Assholes? Easy Thomas' ... Simply drive your beamer across the Mason-Dixon Line till you start running into Idiots!

Mason-Dixon line 

A line in the United States between the North and the South where Yankees go to take a shit and Confederates go to eat.
Rebels head north to the Mason-Dixon line for dinner, while the Damyankees slide south to take a crap.
Mason-Dixon line by Bigyank January 11, 2012

Mason Dixon Line 

The boundary between Maryland and Pennsylvania. A symbolic dividing line between the North and the South before the Civil War. The two surveyors who mapped the line, Charles Mason and Jeremiah Dixon, are the namesake for the imaginary border.
Once you've crossed the Mason Dixon line headed North, you're not likley to find a Waffle House.
Mason Dixon Line by ebradfor November 12, 2005

Mason Dixon Line 

The "mason dixon line" is a common metaphor used to describe a separation, usually directional (north or south). It can also be used to describe other separations such as above and below the waist.
Geographically speaking, one could say: "The mason dixon line separates the yanks (people who stereotype everyone and think the nation should have voted for Kerry or Frankenstein, which ever you prefer) from those who are more refined and choose not to cry about such trivialities as who is the president (he is more symbolic than political anyways).

Mason-Dixon Line Syndrome 

A disease common to people born below the Mason-Dixon line, which restricts each individual's IQ to less than the number of teeth they have. Also referred to as MDLS
So I was watching COPS, and they pulled over a guy with a joint behind his ear. He had a major case of Mason-Dixon Line Syndrome.