When you don't like an Instagram because they have already received "enough" likes. Their Instagrampost is not worthy of your like. You have no more "likes" to give.
Johnny was scrolling through Instagram and realized Sally had a picture of the sky posted, with an ominous cloud. He thinks, I could have watched this on the weather channel and she has already received 89 likes, does she really need 90? Johnny throws Instashade and scrolls past, a sly smile across his face as he judges the next post.
While our lifespan is the number of years we will live, our healthspan is the number of healthy years we will have and our sexspan is is the number of years we will continue to be healthy enough to continue having an active sex life.
A lighthearted reaction upon receiving disappointing news of some sort. Usually something that isn't a particularly a big deal, esp. when it primarily affects someone else - sort of a mild schadenfreude. Sometimes doubled or tripled, and possibly said in a sing-songy voice for added comedic effect to imitate a muted trumpet, which is how the meme originated.