Very, very angry, and probably about to strangle you. It refers to Star Trek's character Mr. Spock, who can be a very pissed off alien if somebody dares mention his human mother, and therefore provokes an emotional reaction in him. It is not, under any circumstances, an advisable move.
First used by Brittany Diamond in her Star Trek TOS commentary.
If someone has to ask about Landrew one more FREAKIN’ time and NOT get an answer, I swear I will go CRAZY like a SPOCK who’s just had his MOTHER insulted.
Ruler of Lake Titicaca. Rumored to have a bunghole that gets very angry if it does not receive toilet paper. Cornholio the Great is often seen walking around with his shirt over his head and his hands in the air, chanting songs about his power, and his bunghole.
"I am Cornholio! You do not want to face the wrath of my bunghole, for I need TP!"
Butthead: Shut up, Beavis! (uh huh huh huh)
Beavis: Um, okay. (heh heh heh heh).