Hoyos Share definition Flag Another word for Big boobs, large tits, etc. Guy 1:"So I went out with this girl last night..." Guy 2:"How'd she look?" Guy 1:"Dude her Hoyos were huge!" Hoyos by Dr.Slang June 12, 2016 0 0 Get merch Get the Hoyos mug. Buy Now — $32.95 See more merch