HowdyDo Share definition Flag HowdyDo - Pronounced, "How-de-do." Popular in Southern life lingo, it means hello while also asking a question at the same time. "Hello and How do you do?" Well, HowdyDo MaryLynn! ! It's so nice to see you again ! HowdyDo by ᴘᴇΛᴄʜ January 3, 2019 0 0 Get merch Get the HowdyDo mug. Buy Now — $32.95 See more merch