To be very inept at something. Mostly used in reference to very public floundering or failure. (Shortened from "having a go at it")
...After that last shot of tequila he started seriously having a go. He tried to get up and go to the men's room but he got tangled upin the chair and took the whole table down. Awesome!
in an awkward situation when you are with your partner and all his friends and you try to make best with his best girlfriend. you ask her if she's having a good time but subsequently making it more awkward!