When a vegetarian or vegan secretly indulges in meat, or when a meat-eater tries to lure a vegetarian/vegan into eating meat.
Lori shakes hands with beef every now and then.

Come on, Lori! (Holding a burger in her face) Shake hands with beef!
by Pink Dog June 7, 2006
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The act of wanking it, jerking off, or masturbating as it is most commonly called.
Im gonna go shake hands with beef before we hit the road, I don't want to have to sperm it up on the way.
by Ginkyzord October 12, 2006
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Hey dude what are you doing?
" I'm gonna go back to my room and get me some hand beef"
by TdogNite July 8, 2015
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