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It is used for a girl with imense , huge , oversized etc. boobs. Usually It can refer to a girl that has very big boobs for her age .
This can be also used for somebody which is very curvy but not fat at all.

G2U can as well be used when refering to the size of the chest.
Ex. 1 Look at that girl, she's totally G2U

Ex. 2 Take a good look at that G2U curves.
by TheRealThings May 30, 2018
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