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Acronym for "Fallacy Until Proven Otherwise." Often used immediately after an individual says something that is hard to believe or flat out absurd
Friend 1: Last night I was at a party and totally laid out this drunk guy

Friend: Yeah whatever that's a total Fupo dude
Fupo by Seebsknowsbest November 26, 2016
Related Words
Fuck U Piss Off

(Fuck) (Fuck you) (Piss off)
Person 1: hey nice haircut

Person 2: fupo

Person 1: No need to get mad.
Fupo by Moosenator May 16, 2016
The clerk behind the counter was such a fupos, he couldn't even make change for a twenty dollar bill.
fupos by JannyGurl May 14, 2006
Brand-name of womens' sanitary equipment geared towards particularly fat upper pussy areas.
Oh, dear. I forgot my Fupon coupon I guess I'll have to buy Pampers.
fupon by Fatngassy May 17, 2007
Damm... Windows XP is a FUPOS!
Fupos by maximo_41 September 27, 2005
The irrational (though understandable) fear of Fupas (fat upper pussy areas). Symptoms include innability to keep food down, desire to end ones life, and night terrors.
I had to go see my therapist about my advanced stage Fupobia. The dreams of armies of post-menopausal women with fupas bombarding my upper body were too much to handle.