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A complete and total wastrel; an emaciated douchebag who says asinine things; a fucking asshole.
My roommate is such a dweezle we have decided to call him Dweezle. Because he fucking sucks.
Dweezle by Tommy Wommy Womsters October 5, 2003

Dweeblerox 

The alien that lives inside the vaginas of whores. Dweeblerox can only survive by getting a necessary helping of penis. Dweeblerox strives to acquire ultimate satisfaction. Unfortunately ultimate satisfaction is unattainable and Dweeblerox will be in constant search for penis, making the whore in question, a whore for life.
Guy 1: Dude, I'm totally going to sleep with Alissa tonight.
Guy 2: Woah dude. You're going to sleep with Dweeblerox?
Guy 1: Dweeblerox? Who's that?
Guy 2: The alien inside her vagina that makes her a big whore.
Dweeblerox by DweebleroxRocks June 22, 2011

dweeblekin 

a person that is so annoying and hideous to look at, yet meek and mild that cajoles you into helping them, then, you regret ever even giving them the time of day because they never leave you alone again.
I hate that she knows my name, she's such a dweeblekin, she made me squeeze three blackheads! Now she texts me every day!
dweeblekin by PapaZee 24 October 29, 2009
the act of a penis becoming flacid during sex with a hot chick do to stage fright.
my best friends was watching me have sex with a girl so i dweedled.
her parents walked in so i dweedled.
dweedle by hooven27 October 28, 2011

Dweedlescant 

A dweedlescant is anyone who is annoying but never picks up on that fact. A dweedlescant is a relentless pest who is often dweebish, nerdy, or is just so caught up in intellectualizing everything that you can't get a word in edgewise. A dweedlescant is usually in his or her teens or is at least as immature as one, if he or she is older. A dweedlescant lacks life experience and often turns to smoking marijuana in later years to help level themselves out, thus fitting in with high functioning intellectuals. There are prescription medications available that have shown promise in recent studies to help a dweedlescant but haven't been approved by the FDA. The lack of approval is partly due to the fact that many dweedlescants have autistic tendencies and there needs to be more research done into the autistic spectrums before deeming these prescriptions beneficial. If you encounter a dweedlescant don't panic, just walk away, otherwise your time will be stolen from you when you are forced to listen to the dweedlescant go on and on about the plight of sea bass and how it relates to nuclear fission and recyclables.
That cafe is packed full of dweedlescants.

dweebler 

a nouveau dweeb (see also dorkand dorker)
Roman is a total dweebler.
dweebler by ensoleillé December 17, 2004