Duker syndrome

A syndrome that effects all people with names that rhyme with Duke.

Symptoms include retardedness, unfunniness and an addiction to flavored air.

Some people with the syndrome can suffer from silly goofiness. They also attempt to pass of the disease by approaching victims from the back and breathing on them silently. If they stand behind you for over 10 minutes without you noticing or smack their nic for more than 10 times in a row please contact a doctor immediately.

Lucas was just officially diagnosed with Duker Syndrome when he sat in his room alone on a Tuesday night smacking his cart.

by Pussyinniolator3000 April 13, 2022

Duke Syndrome

A disease contracted from playing Duke Nukem for an extended period of time.

Side effects include:

- Constant sexual innuendos
- Thinking you're tougher than you actually are
- Swearing. A LOT
- Talking in a low, raspy voice

Joe: Hey man, what's up?
Tim: Go fuck yourself. I'll rip off your head and shit down your neck.
Joe: What the fuck?
Matt: Don't mind him, he's been playing Duke Nukem Forever for 3 days. He's got a major case of Duke Syndrome.

by TheHurriquake June 18, 2011