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Dopesick 

The experience of negative symptoms due to withdrawl from medication, typically opiates (herion, morphine, opium.) Symptoms may include nausea, headache, insomnia and restlessness. The term is not limited to opiate narcotics.
Being dopesick, the only time I've slept in the past few days, is when my body reaches the point of physical exhaustion. Weee!
Dopesick by nocturnal October 29, 2006

dopesick 

In a state of withdrawal usually refering to heroin addiction.
Please man just one fix, I'm dopesick!
dopesick by Ken November 29, 2002

Domesack 

Dome-sack v. The process, usually in gaming, of getting a headshot on someone and places your testicals on their face. This phrase has made its way into everyday slang to also mean to completely dominate/embarrass to an audience.
"Dude I just domesacked that dude halfway across the map with my M416!" or "I just domesacked you on that physics problem"
Domesack by TheHossBoss March 18, 2010

Dopewack 

When something has some dopeness to it but overall it's wack
Bro, that new song is so dopewack!
Dopewack by Tom.thug May 15, 2016

dopesick 

The experience of negative symptoms due to withdrawal from heroin.

These same symptoms are often experienced during withdrawal from other opioids, but someone possessing no experience with heroin ought not use the word to describe their own condition.
"...fuck man i'm dopesick, let's score some smack."
dopesick by get-a-clue March 23, 2010

Big Fat Dope sack

Big fat dope sack is a sack ful of marijuana or some people who take drugs call it heroin. Big fat dope sack is metioned in Dr.Dre's classic song 'Deep Cover'
You: yo is that full of dope?

Them: yeah its one big fat dope sack innit

You: yeah its huge!