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When the funk go down they nowhere to be found, usually think politics are unfair so they get butthurt and D.O (drop out)
Jared who lives in front of grocery outlet in Manteca is a D.O
D.O by SkreezyKeezy209eezy August 17, 2020
Is the most amazing and beautiful entity you will ever meet.

Never gets old and looks like a 16 y/o even if she/he/it's 2882738282828273,67.

He/she/it can do everything so be careful
X: wow, she looks ethereal
Y: i know man, she's d.o
D.o by Mich loves d.o October 15, 2018
D.o is the most amazing and beautiful entity you will ever meet.

Even if she's 2882738282828273 she looks like a 16 y/o

She can do everything so be careful.

Has the same pronunciation of God in italian: "Dio"
×: omg she's so beautiful
Y: i know, she's d.o
D.o by Mich loves d.o October 26, 2018
Doctor of Osteopathic Medicine
Person A: "Are you doctor...an M.D.?"
Person B: "Yes, I'm a doctor, but I'm a D.O.!"
D.O. by ctak July 16, 2006
This usually means Depression and Obsession like the song “Depression & Obsession” in the XXXTentacion album “17”
d&o by Youngdaggerdiiiiick January 4, 2018
To punch someone excessively hard, breaking the top of their jaw with one swift move.
Kyle: *Punch to face*

Devin: *Face broken*

Crowd: "yo he got D.O.'d"
D.O. by spiderdude9 May 7, 2011