An expression used to indicate that one finds a female reasonably attractive. Literally means that given the chance, you would like to engage in anal intercourse with her.
Britney: "Dad, I'd like you to meet my boyfriend, Kevin."
Dad: "Nice to meet you, Kevin. Now I want you to take good care of my daughter. She's a beautiful young lady and you should treat her with the respect she deserves."
Kevin: "You got that right, Pops. I'd throw it in the two hole. Can't wait to chuck my junk in that."
Dad: "Excuse me?"
Kevin: "Hey old man, you got a shitter around here? I got fuckin' plastered last night at the strip club and I've got some wicked beer shits."
(adj.) The state of being in which one finds themselves broke, drunk and loitering on the front porch of local store in a Bush Alaska community. Totally, completely, utterly...F'd in the pants!
Ughhhh. my biographical poet paper is "f'd in the pants!"