by Edubb23 March 02, 2019

by RedHood115 February 01, 2017

"Yeah I know David has autism but we're chill, he's my chromie homie"
"That special ed kid is my homie with an extra chromie"
"That special ed kid is my homie with an extra chromie"
by TheRollexWatch November 28, 2016

The most powerful, super group of speeds to ever roam the world! Their quest is to rid the world of all things Gay and eViL. The Chromosomes will live on! With their Captain, The Helmet, Tourette’s, A creature known as WWW, Anyerismo, Mr.Chromtastic, Downy Boi, and The Caretaker(who is the only normal person in this stupid ass group). Together they will stop all evil and get rid of the gay(and Helseth)
Oh Shit! The Chromie Homies are here!
by YourFriendlyNeighborhoodFaggot June 18, 2018

by fffaaahanhh March 21, 2022

by Rent a car place January 31, 2019

People who have extra chromosomes and are best friends. "Chromie" referring to chromosome and "homie"s referring to " people who are good friends and would die for each other".
People who have extra chromosomes and are friends are considered extra chromie homies. Yesterday, John and I went into the extra chromie homie room by accident.
by B4dg3r January 12, 2017
