1 in 4 club

Those with genital herpes. This is a reference to the fact that 1 in 4 people has genital herpes.

Joe: I went on a date with Karyn last night.
Mark: Dude, she's in the 1 in 4 club!
Joe: I won't be dating her again!

by 2014_chiguy May 4, 2008