Top definition
Those with genital herpes. This is a reference to the fact that 1 in 4 people has genital herpes.
Joe: I went on a date with Karyn last night.
Mark: Dude, she's in the 1 in 4 club!
Joe: I won't be dating her again!
by 2014_chiguy May 04, 2008
Get the mug
Get a 1 in 4 club mug for your barber Jerry.