[up in smoke] 

the greatest movie in the world youll laugh your ass off.its a really funny stoner movie.cheech and chong are ausome!!!!!!!its funny as shit!!!!!!

in up in smokea police officer stoped cheech and chongand cheech ate their joint the officer asked what were their names?
cheech:uh his name is
chong:ruhhhhh!! (throws up)
cheech:rrrraphl
its funny

[up in smoke] by whycare April 25, 2007

Up In Smoke 

Where my money goes.

Up in smoke, that's where my money goes, in my lungs, and sometimes up my nose.

Up In Smoke by the st[one]r August 6, 2008

Stoked, stroked and up in smoke 

A euphemism for blue balls or the female equivalent. Stoked about getting it, stroked for a little while, and then it all goes up in smoke and nothing happens.

"Man, last night blew. Stoked, stroked and up in smoke."

Stoked, stroked and up in smoke by Lanikai July 18, 2009

up in the smoke 

up in the smoke means when you smoke lots of weed get high and the room gets really smokey .

“Hey man were up in the smoke “

up in the smoke by Stayout March 16, 2019