DUFF

Designated Ugly Fat Friend/Designated Ugly Fat Fuck/Dumb Ugly Fat Friend

The infameous beer that Homer Simpson drinks on The Simpsons

a teenage pop star who has some talent but is over shadowed for being a "poseur"

That girl is a TOTAL DUFF

Homer Simpson always drinks Duff beer.

Hilary Duff is alright but everyone calls her a "poseur"

by Mike December 28, 2005

Duff'd

Duff'd (v) - The act of getting used and or manipulated by an attractive, mentally unstable person of the opposite sex. Unfortunately this includes an abundance of flirting, profound mixed messages, and sexual enuendos that don't actually lead to SEX, merely the illusion that it will. The Duff usually ends by the Duff-er getting back together with their original girl/boyfriend, leaving the duff-ee with a killer case of blue balls/dry-gina.

Man, I thought this relationship was going to go somewhere, but really I was just totally getting Duff'd!

by DFaFH April 25, 2006

duff'd

when ones pancreas explodes (from duff mckagan of guns n' roses)

dude i was wasted last night i fucked like 4 chinese prostetutes then my pancreas duff'd

by Caflisch22 May 5, 2006

deffafeffer

1.) A word that has the same definition as the word definitely, with one crucial difference: it is/sounds over 9000 times more awesome

Fuck yeah seaking, I deffafeffer went over 9000 last night with Maggie

by GBorGH November 26, 2010

duffas

A boy who hits puberty way to young, and resembles a grown man by the seventh grade, who wears a taped pair of glasses and trips on him self often.

Hey you see that duffas over there trying to pick up on that chick, I bet he'll lose his balence in five seconds, lol!

by joe May 18, 2004

dufferz

Dufferz - my nickname, my name being Sam Duff.

Also commonly used to say damn, dufferz loves his milf! lol

Boy, that Dufferz is so hawt!
Kerry fancys Dufferz

by Sam Duff December 15, 2008

deuffer

The meaning of deuffer is anything you can take any word and replace it with deuffer.

That guy stole my bike what a deuffer, or a surprise birthday party! you guys are so deuffer.

by Keifer W.G January 15, 2008