Adjective

-Showing signs of beeing stoned,when you havent ever even touched a bag or leaf of pot, acting stoned talking like your stoned,walking like your stoned,and thinking like your stoned.
A: Dude you are so incredibly tweeked its not even funny.
B: Huh, Huh..wait.. wut?

X:Hey you two, i dont want you tow crazy hippie stoners haning around here anymore!
Y: Oh no mr.wong we're not stoned we're just tweaked.
Z:Yeah man, totally umm like totally nothin to worry.uhh whats that word a ground around..uhh dammit i cant remember.
Y:ha ha hah ah, dude i think your trying to say about..hehe lets go get a milkshake
Z:sweet to the max
Y:later dude
X: crazy stoners...
by mcbar May 8, 2005
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An act of picking on someone caused by anxiousness for another high.
If you catch anyone tweeking, they're drug of choice is controlling 'em.
by Mr. Terrence L. Trezvant June 4, 2007
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to send a tweet in Greek
Hey did you see Matt's tweek? What did it mean?

Yeah, he told Amy how awesome the flaming cheese was in Greek... I google translated it.
by greektweeker February 1, 2011
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Also known as a foursome or orgy; Tweeking is when four participants of either the male, female or unspecified genders participate in fornicating with one another at the same time.
Ryan: Hey, you wanna' go tweeking?
Tweek: I'm in.
Chez Mix: Oh wait, Batman's not here. We need another person.
Tweek: God dammit.
by Batman>:( November 14, 2011
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to be forced into smiling by infectious enthusiasm and boundess energy
you've been tweeked, i was at a low until i got tweeked
by gsxrboy June 2, 2007
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Generally used as a verb to refer to what a DJ does to the knobs on the mixer.
Did you see that DJ tweek the knobs?
Tweekin' the knobs!
by katze April 19, 2005
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