the state of mind when using methamphetamines that the user cannot stop doing an activity and has been up for days.
Man i was tweeking hard after cleaning for six hours last night.
by Tweeker July 17, 2003
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losing oneself in a senseless task while under the influence of speed.
She would tweek all night cleaning the house and pulling apart electronic devices.
by chillcat May 30, 2003
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the nervous ticks or twitching one experiances as they come down from a crystal methamphetamine binge.
pulling hairs out of their face; picking at their face; picking their nose...
by a former tweeker November 28, 2003
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To be in paranoia or panic
"Dude, no one is talking about you so stop tweeking."

"Just because you're alone it doesn't mean someone is watching you, so stop tweeking."
by Melisha June 25, 2005
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