This is a character for a TV series named "SouthPark" This character is twitchy and is always drinking coffee and blurting our noises and conspiracies. He is also in a homosexual relationship with Craig Tucker after tons of people loved the slash so the creators made it happen.
Craig: You should stop drinking coffee Tweek.
by IsYaBoiSam May 01, 2016
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Gay. Twitchy. Spaz. Loves Craig, Kenny. An adorable bean. GAH!
“Oh my god, Tweek and Craig are holding hands” gasped a random person on the street
by ThatSouthParkYaoi July 01, 2018
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A smol chubby talented gay babey.
Appears on southpark. He's addicted to coffee and meth, and loves to play the piano. He's a good singer.
He and Craig Tucker are a couple. Like I said earlier, he gae.
TweekXCraig is my favorite episode!they were so gay in it! Especially Tweek!
by The_emo_bunny_ August 09, 2019
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A character from the T.V show "South Park". He has very messy blonde hair and supposedly sufferes from A.D.D but his twitching and nervous personality is due to the large amounts of caffeine he consumes. In Series 6, Tweek became the main characters replacement for Kenny, alongside Butters, after he "permeanantly" died at the end of the previous series.
"Tweek's the worst character ever."
"Yeah. Worse than Towelie."
by Issy Aidsfunop January 15, 2006
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Similar to a Gleek, the Tweek is the Twilight version. Geek + Twilight = Tweek
OMG I am sooo excited to go and see the new Twilight movie, I'm such a Tweek!!
by Sazilicious July 02, 2010
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Someone who Twitters obsessively on the social networking site "Twitter." Twitter + Geek = Tweek. Often appearing to be normal people on the surface, they will quickly reveal their inner geek whenever anyone mentions Twitter in a conversation, at which point they will tell everyone within earshot about all the hilarious and uninteresting things their friends and acquaintances have recently tweeted about.

See also "Twatter", someone who tries to accumulate a large following on Twitter in order to hide the fact that they are actually a giant twat.
Rational human: "I can't believe CNN is reporting on what politicians are tweeting from the halls of the Senate...or that politicians are tweeting in the halls of the senate, for that matter."

Tweek: "OMG I LOOOOOVE TWITTER!!! My friend Jessica just tweeted about how the guy next to her in line at the DMV just farted and she said it smells like a mix of hot garbage and a yeast infection!!! How funny is that?!"

Rational Human: "I hate your face."
by thepoolboy October 05, 2009
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To pinch or flick...

"I tweeked her nipple and she tweeked my clit with her tongue."
by Junebug December 14, 2005
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