He's so tweaked out.
by kush_ March 16, 2005

Out of sorts, or on drugs.
by Billy March 11, 2003

by Peter Tweaker August 06, 2003

by Malkim El-Shabazz September 24, 2003

by Gordo352 April 22, 2006

twisted generally related to events perceived while on hallucinogenic drugs, usually referring to an individual.
"Man, last night I dropped five microdots and ran up primrose hill naked! Boy was I tweaked!"
"I was out for a stroll on primrose hill last night and I saw a naked guy running around. He looked HIGHLY tweaked!"
"I was out for a stroll on primrose hill last night and I saw a naked guy running around. He looked HIGHLY tweaked!"
by Simon November 09, 2004

by J April 06, 2005
