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snakes on a mother fucking plane 

The excited way of describing one of the most hyped movies of the summer, Snakes on a Plane. Used by Samuel L. Jackson in an interview with Jon Stewart.
"Yes! Snakes on a mother fucking plane!"

Snakes Hiss 

Cockney Rhyming Slang for Piss
Watch my pint mate im off for a Snakes Hiss.
Snakes Hiss by Gareth Tattersall September 12, 2005

snakes on a plane 

A simple existential observation that has the same meaning as "Whaddya gonna do?" or "Shit Happens". Taken from the upcoming Samuel L. Jackson movie of the same name, and immortilised by screenwriter Josh Friedman on his blog post of Wednesday, August 17, 2005.
Guy 1: (irate) Dude, you just ran into the back of my SUV!

Guy 2: (calm) Snakes on a plane man. Snakes on a plane.
snakes on a plane by Case Smith September 9, 2005
Word of the Day on August 18, 2006

snakes in her head 

When a good looking woman is downright insane. Affects all women to some degree. Any involvement with such a woman is to be handled with extreme care. More advisable to just stay clear.
"Dude, that chick was hot! Why'd you dump her? Was it the whiff factor?"

"No, she passed the whiff factor, she's just got snakes in her head. I wouldn't touch that with Lundberg's dick."
snakes in her head by ATMofMN March 11, 2010

snakes & ladders

A classic children's board game played between 2 or more players on a playing board with numbered grid squares. On certain squares on the grid are drawn a number of "ladders" connecting two squares together, and a number of "snakes" also connecting squares together. The size of the grid (most commonly 8×8, 10×10 or 12×12) varies from board to board, as does the exact arrangement of the snakes and the ladders: both of these may affect the duration of game play.

Snakes and ladders' simplicity and the see-sawing nature of the contest make it popular with younger children, but the lack of any skill component in the game generally makes it less appealing for older players.

What's the name of the game that we are playing
Boy whenever I think that we are winning
Then you roll the dice take a slide
Right back to the one from 99

Is it gonna go on like this forever
Are we gonna to take that last step together
Going round and round and up and down
Feels just like snakes & ladders
snakes & ladders by NiyaF August 5, 2007

Snakes to ya 

In reference to Snakes On A Plane, an expression of sympathy for a bad situation. Another way of saying "that sucks."
Michael: Dude I got Alaskan Pipe Bombed last night.

Aaron: Snakes to ya bro.
Snakes to ya by Mr. Stanturf June 12, 2011