John: Man, i'm feeling really down since my break-up.
Dave: Maybe we can hit the clubs and take your mind off it.
John: Maybe, i could use A pick me up round.
To raise one's pants from ankle-level to waist, covering the nether regions; opposite of drop trou.
My buddy dared me to drop trou in front of a group of schoolkids. It was really embarrassing when the police officer told me to pick up trou before I was arrested for sexual harassment.