(n) The tragic failure of an idiot who left cream cheese in her fridge, went away on spring break, came back, and tried to clean out the explosion into the trash can on the floor of a dorm. It caused many deaths, and destroyed the smell of the floor.
Senior:...it smelled as bad as the Cream Cheese Incident of '09!
Junior: Whats the cream cheese incident of 09?
Other Senior: (falls to the ground in state of PTSD)
Referring to a person who constantly and sometimes unintentionally just annoys the fuck out of the people they are around. Implies that they melt your head.
Joe: ah no, look who just arrived!
Mitch: Shit, that lad is such a Ham and Cheese Melt!