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She is a fat ass bitch. Normally looks like a bag of onions, or potatoes and is always eating all the honey buns! Obese of course, and has type 20 diabetes. She always cheats and has a dry ass wig on the top of her head. Normally gets big headed folks, and starred in the movie Madagascar as the hippo, Gloria!
Vaughn! Wheres all the honey buns??

"Oh, that fat bitch Yayo ate them all."

Omg Yesterday my brother ate so much at dinner!
"Ew, tell him to stop being a Yayo."
Yayo by Alaya's World! December 15, 2018
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Relating to the English term hello
Yayo, how ya doing neighbor
Yayo by BxxbbbyyyJ January 1, 2022
This word became popular after rapper E40 made a song about it. now i cant say he started using it first, but he had a popular song around 97 called "slangin yayo".

it is true that it first appeared in scarface, but i never saw people writing "yayo" before e40.

he is from the san fransisco bay area and sometimes the "east bay" is reffered to san yay. anyway, getting back on point yayo means cocaine.
i hope i dont go back to slangin yayo-slangin what-- yayo-- to get my mayo.

mayo = money
yayo by mooseboy84 August 12, 2004
Yayo is the spanish word "llello". To make it easier for the english people to pronounce it properly they said "yayo". It sounds the same thing is spanish so STOP TRIPPIN!!!!!!
Man yesterday i sold an ounce of that yayo.
yayo by Brandon October 3, 2004
A slang term for the narcotic cocaine.
i ran three miles after hitting up that YaYo party last night.
YaYo by demtris October 1, 2006
Used commonly by some as an expression of concurrence or in a celebratory manner.
Hector: Hey Skinny d, are you going out tonight?
Skinny d: Yayo!
yayo by lanceddd April 26, 2008
-Cocaine also known as coke.Often a term used bya thug or gangster.
-It is actually a spanish word spelled llello, however, it has been,like many other words, americanized.
Example:
Thug- Yo dawg , can you hook a g up with some yayo?
Thug's homie- Yeah dude, how much you want?
Thug- About a gram yo.
yayo by bizel October 8, 2005