Top Definition
1. Short for Mayonnaise, a thick, creamy sauce or dressing that is made of vegtable oil, egg yolks, lemon juice or vinegar, and seasonings.

2. A rural county in the West of Ireland.
"Pass me da mayo, Jayo"
by Maddzy August 12, 2004

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A derogatory term for whites people a.k.a. bleachers, honkeys, whiteys,, and cracker.
It is more commonly used in the context of when food is involved in the conversation.
Do we have any salt for the water?
No you mayo, go jump off a bridge.
by Dragon Slays That December 12, 2010

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This term Mayo is used to describe the act of smoking a cigarette down to the filter, where there is virtually no tobacco left.
Bill: Hey man can I hit that cigarette?
Bob: There's only a little left.
Bill: It's fine I will just Mayo it.
Bob: Fiend.
by keylimeisbomb February 28, 2013

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mayo
1. a (noun) meaning a man with an overwhelming desire to have an extreme amount of sex. mayos are known to be very well indowed and make excellent boyfriends as well as lovers.

2. a (noun) mayo is a thick white substance, some people spread on sandwhiches. made from oil, eggs, vinegar and seasonings.
1. "mayo and i have amazing sex on a daily basis!"

2."i want some mayo on my sandwhich please."
by herbalangelkc February 04, 2010

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A small town on a peninsula just outside Annapolis, Maryland. Masters at beer pong, tubing/wakeboarding, and partying. You can find marijuana on almost every teenager over thirteen. Don't be to surprised by their abusive, vulgar, and often threatening language/behavior or if every white person you meet acts as if he were black. Also see Edgewater.
Out of Towner: Where the hell did you get all that weed?
Mayo Resident: Yo, where else but Mayo cracker? I won it kicking some white son of a bitch's ass at beer pong while at the sickest party EVER.
by sarababeee September 24, 2008

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A common nickname for the name "Maya"
-"Who's the new girl?"
-"Oh thats Maya, but everyone calls her mayo"
by Mayo19 March 29, 2015

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verb.

when a man or woman is sexually aroused and releases a creamy sticky white substance from the genitalia region. see semen.

noun- the substance released.
while watching 2 girls 1 cup, simon mayoed everywhere.

why would you leave mayo stains on your bed?
by juddyyyyyyy July 10, 2008

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