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To space out intensely while under the influence of some sort of psychotropic drug.
Guy 1: *spacing out, drooling*
Guy 2: what's wrong with you?
Guy 1: huh?
Guy 2: Dude you're tweaking.
tweak by Fishmanist January 9, 2010
Related Words
It's YOUR brand, do what ya' gotta do!
Dude, I helped TWEAK design a shoe!

The TWEAK Rhett & Link Mythical Shoes are the coolest shoes ever check them out!
TWEAK by TWEAKfootwear April 22, 2011
To give a girl's clit a real workout, I mean, like when you give it the rub-a-dub taking it between your thumb and index. Not to be confused with mere twiddle.
I was giving her a real tweaking when her mother walked in on us.
Tweak by Hugh G Rection October 7, 2003
A kid who is shaking or just twitches all the time. Common name for kids who move with speed for a second or 2 for no reason at all. Mostly they call them "tweak" in high school. They just jolt for no reason.
"Nelson was a tweak, he drank sugar water all the time". During clas he tweaked out for no reason
Tweak by mike July 5, 2004
Tweak=ian look all around culver city marina del rey and santa monica so see it hit up all over the place
Oh shit look some one hit up Tweak!
Tweak by tweak(ck17) May 27, 2003
–verb

1. To get very angry or randomly mad
2. To freak out
3. To yell

May also be seen as:
Tweak'ing
Tweak'er
Tweaking Balls
"Yo she's tweaking balls"
"What's with all the tweaking?"
"He's a tweaker!"
Tweak by Tehbs. July 7, 2009