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Main Squeeze 

Referring to the main woman that gets you to ejaculate so strongly that your engulfed prostate promotes an involuntary spasm of your gluteus maximus.
Having sex with my hoe is cool but it's nothing compared to sex with my main squeeze. For example, when you're hungry, you get that fast food and it does the job but it's nothing compared to that restaurant-style filet mignon.
Main Squeeze by Wor Izzo November 22, 2020
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main squeeze 

“yo peter is my main squeeze

“that wasn’t very main squeeze of you”

crank that by soulja boy is main squeeze”

“stephanie and stefanie are main squeeze”

MAIN-SQUEEZE 

The girl/woman you'll always have strong,intimate feelings for. No matter what. The person that gives you unimaginable drive to do whatever you set your mind to. Who makes you unbelievably happy and makes your butterflies' butterflies' have butterflies. The person who you have no problem completely opening up to. A person who's your girlfriend and your bestfriend; who you can tease and get made fun of back and it's completely and "toats" "k". It's a person who instead of saying you automatically felt a spark/connection with, you say you felt fireworks. It's simply that one and only ultimate other-half. That one person, that you know, has changed your life for the better. "Simply Because..."
Randy: Man.
Dominic: What?
Randy: Jasleen Bain's is my Main-Squeeze. Without a doubt.
Dominic: Yeah, I can tell.
Randy:It's no secret. I'm proud to say it. To everyone.
MAIN-SQUEEZE by DINGLEBERRY ;] October 20, 2010

my main squeeze 

Your best friend, home skillet, buddy for life, homie home dog, home skillet biscuit, friend for life,usually of Mexican heritage, around 5 feet tall, often named Andrea because you guys are BFFS and he/she is the real MVP. All in all, your uber duper extra best friend.
Yo that girl Andrea is my main squeeze, we been friends since all the way back in 2010

jack my main squeeze 

jackson is a cool kid and he likes to send memes especially about the holocaust he is a terrorist and is apart of the mafia and likes to rape young children.

Main Squeezie 

Best friend of yours

mainsqueeze 

Like a boyfriend.
Or used also as a term for friends.
"Aye though do you got a mainsqueeze?"
"I'ma kick it with my mainsqueezes later."
mainsqueeze by ohwowsapalooza April 28, 2007