A cousin of the term Anaconda, the word Python also refers to a dick.

Someone who says they like Python is actually trying to hint to you that they enjoy dick.
As a statement of truth: "I have a huge-ass Python"

As a pickup line: "My python's very happy to see you"

As a euphemism for liking dick: "I like Python"
by OVERLORD11 February 1, 2011
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Monstrous, possibly apocryphal constrictor snake alleged to dwarf both the prehistoric Titanoboa and the supposed Amazonian Megaconda. Claimed to grow to 200ft in length and several feet thick. Name derives from a fusion of python and Terminator (James Cameron film franchise). Thought to frequent Polynesia.
The Pythonator could be capable of devouring whole elephants
by Slitherhippy February 6, 2009
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another way to describe the unholy size of a males genitals to intimidate and prove their dominance along with showing their alpha presence. most notable in guys named Blake and sam
by G$420 October 7, 2019
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Inserting a dangerous snake up someone's ass before performing anal sex.
After a wild weekend of Python, Gary was bitten on his ass cheek and later died of his wounds.
by dangling_participle August 12, 2011
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Eating way more food than necessary at a meal, with the intent of stocking up so not to have to eat again for a long time.
P1: "The department is hosting a seminar today at 12:00pm in the science building foyer. There will be food..."

P2: "Sweet, I'm pythoning it up hardcore"
by The Fano April 16, 2008
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To get owned or pwned. To take advantage of and make something your bitch
Jacob just totally pythoned that Access Database!
by BrianIowa April 18, 2008
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Python, see Monty Python
note: Python is usually used to refer the Flying Circus, rather than the movies, such as 'The Holy Grail', or 'Life of Brian'
Python Pictures presents.... something completely different! (Cue theme)
by Chris L. December 27, 2003
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