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Shitballs

General statement of amazement or disgust.
"Holy shitballs, Jim! Did you see her ass?"

or;

"Holy shitballs, those are some nasty-ass pubes."
by Justin Herbert December 9, 2008
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shitballs

An overwhelming feeling above any others you may have previously experienced
Holy Shitballs!!!! I got free tickets to go see slayer live in concert!!!!!!!
by Thrash Is Back February 17, 2008
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SHITBALLS

often followed by !!!, SHITBALLS can be used as an exclamation for anything.
Me: SHITBALLS!!! That kid is really ugly
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Shitballs

When a guy wipes from back to front after taking a crap and gets shit on his balls.
OH CRAP!!! I wiped the wrong way. Now I have Shitballs.
by Ferret79 June 28, 2007
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Holy Fucking Shitballs

N. An expression of surprise describing the process of getting piss drunk, then fucking a transvestite hooker, and waking up with shitballs in your ass. In conjunction with your hangover, you may find yourself either good surprised, or bad surprised, followed by the realization that holy shit your wife is going to be home in ten minutes/this bastard just fucked your wife/you're fucking gay.

Etymology - Derived from holy fuckballs, changed the word "fuck" from its verb/adjective case to a pure adjective to modify the word "shit", which, when added onto the term "balls" describes a penis that has recently gone through anal sex without a condom. Hence, "shitballs". Other variations include "shitdick" and "shitcock" and "shitwang" and finally, "shitpenis".
Holy Fucking Shitballs!

Who the fuck are you?
I'm gerry, remember me? We just had hot, sweaty, nasty anal sex.
Holy Fucking Shitballs
Hell yeah man, priest fucked me real good round about when I was ten.
by fuck you, the mighty fucker! October 17, 2010
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Shitballs

Something yelled when things aren't going your way.
Guy#1 I wanna fuck your sister!
Guy#2 She moved to Alaska last month, you dumb fuck
Guy#1 SHITBALLS!
by ShmexyBoii October 28, 2011
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Shitballs

A verb, meaning to go crazy or to lose the shit off of your balls.
Mainly used when someone says something extremely obscene.
Kate: Wanna have sex?
Bubba: SURE!

Kate: Oh yeah, I just had my period.
Bubba: FUCK! Don't go shitballs, bitch.

"i woke up this morning with the shitballs again"
"went out earlier and started talking to a girl, what do you know her friend straight up shitballs me!"
"I once took my girlfriend to a shoe store but when she told me to buy her shoes she straight up shitballs'd me"
"John left his shitballs in my backseat again, i'm going to have to call into work again"
by GottaLoveCorn August 23, 2012
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