diffy

A slang term for clostridium difficile. Clostridium difficile has a very distinct smell.
Yo, did it smell diffy?
by ludawgg1234 March 12, 2015
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Diffy

DIFFY: : lacking needful or desirable substance : weak, ineffectual.

Another word for: Retarded, Lame, Dumb, Boring, Stupid.
"Hey, dude. You going to Nate's party tonight?"

"I don't know, ,man. Last time I went over there it was pretty 'Diffy'."
by Metal Metal Rob Walsh August 28, 2010
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Diffy

A person from the capital of Mexico. D.F. Districto Federal.
OMG did you see that diffy cross the border?
by Stephro February 23, 2009
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Diffy

A diffy is a term people use when they are high on drugs (any kind) an have a sudden urge to lick a butthole.
Jones: Wow, these drugs are really making me want to do a diffy right now.
Slim: I agree.
by Barstars905 July 17, 2016
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Diffy in the jiffy

Used commonly as slang in the modern videogame League of Legends, popularized by a Twitch streamer Tarzaned and many others, when one of the players in one of 4 lanes (Botlane, Midlane, Toplane, and Jungle) hardly underperforms in the Jungle role or gets outplayed by the enemy player several times, causing the game to be lost before 20-minute margin.
Yassou: Oh no! We have Nightblue3 on our team
Sanchovies: Diffy in the Jiffy it is...
by Chrive May 29, 2020
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diffy-q

Mathemtician Slang:

A differemtial Equation.
Yo son, did you use the Wronskian on that mutha fuckin' ass diffy-q?
by Skandal Jack March 09, 2005
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diffy-q

Doood! Diffy-q's are suck!

Translation: I'm stupid.
by meselfs January 12, 2005
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