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Wi-z-uhl (noun) A sickness in which a person needs friends or they will shrivel up and die; a person with sad sickness.
Hey Wizzle! Do you need me to be your friend right now?
Wizzle by The Master Wisdom November 24, 2010

holy shiz wizzle 

Holy shiz wizzle... I don't believe it!
holy shiz wizzle by Cat May 13, 2005

smizzle the wizzle 

this means quite literally to smoke the weeed man. usually used in a kinda way that only pot heads look forward to sayin. hey any chance to smizzle the wizle is a great chance for anyone.
yoooooo man.........um u wanna....smizzle the wizzle and get fumando!!!
smizzle the wizzle by PISAN December 2, 2004

Buck Wizzle

To go Buck Wizzle is a term used to in AY town, Bucks, and is used to describe a state of going wild, usually when pazza. When going Buck Wizzle, one generally has no consideration for anything or anyone, and does not care who is harmed in the process of going buckers!
Ima go buck wizzle tonizzle!

Getting buck in Bucks!
Buck Wizzle by DWR08 May 12, 2008
To urinate whilst fighting back an alcohol-induced malaise.
I wizzled more on my shoe than in the urinal.
wizzle by John Steinbeck March 28, 2003
Installment in the -izzle language that pertains to words beginning with 'W'.
- Weed is by far the most common usage for 'wizzle'.
Sizzle (smoke) that wizzle (weed), before you get your ass kizzled (kicked).
Wizzle by Diego November 26, 2003