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uncle loser 

an uncle louie sized loser who has a big ass and a skinny weiner.
god your zuch a uncle looser! just leave!
uncle loser by acetic August 19, 2003

boozer loser 

is a person who habitually drinks & gets sick therefore ruining the night for everyone else involved
"Kelly's such a boozer loser she's only aloud to partake in shirley temples when we go out as to avoid another trip to the car wash"
boozer loser by lilpiz October 6, 2009

Genetic Lottery Loser

A person who failed at the genetic lottery so badly that it's actually sad rather than funny.
"The genetic lottery. You only get one shot at it. Some people hit the jackpot. Others...Don't."

"My mate is a genetic lottery loser. He's lived a healthy lifestyle his whole life and is still overweight, and he's been single his whole life due to his social anxiety and numerous skin problems. He just wants to be loved or at least accepted, but it's proving to be impossible because he looks like a loser even though he's trying his best. Guy needs a hug."

fucking loser 

Matthew J. Geragos
fucking loser by Anonymous August 27, 2003

skinny loser

A skinny loser is a person who thinks that they deserve a pretty thin girlfriend or boyfriend soley based on the fact that they are thin. Most are tattooed,uneducated.poor, wage slaves,who have this undeserved sense of entitlement because they are thin. A skinny loser usually does not have trouble finding a date because of their thinness. They could be dirt poor with a criminal record but they will still have the basic necessity of life, a partner. All because they are thin. They may be very unattractive but society rewards them simply because they are thin. The only thing they have going for themselves is that they are naturally skinny. These people do NOT exercise at all. In fact, a skinny loser eats like a pig but is blessed with a fast metabolism thereby maintaining a normal weight. These people feel superior to their obese counterparts simply because they are naturally thin. They believe that they deserve the finer things in life just because of their thinness. Our society further perpetuates this idea by rewarding thin people, especially white people.
skinny loser by ameerod January 16, 2010

Holiday loser 

One who, despite having an abundance of friends and family, finds himself inexplicably alone on major holidays (esp. at Christmas).
Damn, I should never have spent my last 500 dollars on that prostitute last week. Now I can't afford the airfare to go home for Christmas. I'm always such a holiday loser!
Holiday loser by Trebor1970 December 23, 2008