duff 

A woman pregnant. Also the name of an Irish winger at Chelsea

She is up the duff

duff by Britboylangers May 21, 2004

Duff 

To be the ingenue. Derivitive of actress Hilary Duff

"Only a total Duff wouldn't stand up for herself after being publically humiliated."

Duff by Regina F. October 9, 2005

duff 

as in to bone a chick. to get duffed out

i duffed this sweet dude last nite yeahhh!!!

duff by gap slammer November 7, 2006

DUFF  

Desiganted Ugly Fat Friend. A common acronym used in male cliques. Used to refer to the girl that the "hot chicks" bring along to distract the "Wingman" (every male clique has one, his job is to intercept the DUFF.) so the ycan have the more desirable males of the group.

"Dude, you sooooo got the DUFF tonight."

DUFF by TXwolfman817 February 24, 2009

Duff 

V. To plan a sexual encounter and back out soon after, to stand up.

He said he wanted to be with me, but then he duffed out and changed his mind.

Duff by Laurie-Bell February 1, 2009

DUFF 

Deluxe Ultra Freaky Friend

man, that girl looks like a DUFF

DUFF by jdizzowizzo May 2, 2009

Duff 

An alternate name for penis.

"He wants to put his duff where?"

Duff by TeamTripod July 8, 2009