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Take it in the ass 

1) To express disappointment
2) Slang expression for an unfair/unfortunate event
1) Jeremy took it in the ass on that.
2) Paul took it in the ass when he invested in Worldcom stock
Take it in the ass by BIATCH551 March 15, 2005

Pain in The Ass

My nephew
Someone who annoys the shit out of you for no reason
Pain in The Ass by Ally Shaw June 23, 2016

crab up the ass 

an emotional state usually combining anger, annoyance, nervousness, or pain, in which the person is generally in a bad mood
She was acting like she had a crab up her ass after she didn't win the prom queen nomination.

dont know your ass from the ass end of a bowling ball 

dont know your ass from the ass end of a bowling ball similar to dont know your ass from a hole in the ground a little more funny
you mister president dont know your ass from the ass end of a bowling ball

Paying out the ass 

Something you will pay a ridiculous amount of money to rent, buy, or repair/maintain.
"I just bought a used 1987 Porsche 944 Turbo...looks cool, but I know I'll be paying out the ass to do repairs on it!!"

holding it up the ass 

When you have a big turd hanging around your anus, but you refuse to let it out.
Billy was holding it up the ass in class today.