1) To express disappointment
2) Slang expression for an unfair/unfortunate event
1) Jeremy took it in the ass on that.
2) Paul took it in the ass when he invested in Worldcom stock
by BIATCH551 March 16, 2005
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Haha! You take it in the ass! Nya nya nya nya nya
by iopq November 12, 2003
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My boss is treating me like shit, but I'm not gonna take it in the ass anymore.
by Mower420 March 28, 2020
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A phrase used to express a persons sexual preference to have a penis inserted in their ass. They usually like it too.
Hey, there's Charlie. He takes it in the ass!
by Professor Socrates August 5, 2005
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When someone takes good natured kidding too seriously and/or personaly.
Damn man! Don't take it to the ass, I was just messin' with you!
by Pedrick Jones April 28, 2007
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