To be the life, and subsequent death of the party. Usually accomplished by bringing ample amounts of goon and sharing it with all your friends. Keg costume is preferred, but not essential when Isaacing.
Oh man, Griffgot so shitfaced at the end of year party, he was Isaacing all over the place
Ruler of Lake Titicaca. Rumored to have a bunghole that gets very angry if it does not receive toilet paper. Cornholio the Great is often seen walking around with his shirt over his head and his hands in the air, chanting songs about his power, and his bunghole.
"I am Cornholio! You do not want to face the wrath of my bunghole, for I need TP!"
Butthead: Shut up, Beavis! (uh huh huh huh)
Beavis: Um, okay. (heh heh heh heh).