CognitiveFuel's definitions
2-Chloromethylthiophene is used as an intermediate to 1-(2-thienyl)-2-Propanone.
In a 2-l. beaker surrounded by an ice-salt bath , and fitted with a mechanical stirrer and a thermometer, are placed 420 g. (392 ml., 5 moles) of thiophene and 200 ml. of concentrated hydrochloric acid. A rapid stream of hydrogen chloride is passed continuously into the mixture with vigorous stirring. When the temperature reaches 0°, 500 ml. of 37% formaldehyde solution is added at a rate that will permit the temperature to remain below 5°. The addition requires about 4 hours. When all the formaldehyde solution has been added, the mixture is extracted with three 500-ml. portions of ether. The ether extracts are combined, washed successively with water and saturated sodium bicarbonate solution, and then dried over anhydrous calcium chloride. The solvent is removed by distillation, and the product is distilled under reduced pressure through a 50-cm. fractionating column. The product boiling at 73–75°/17 mm. is collected. The yield is 257–267 g. (40–41%) of a colorless oily liquid.
In a 2-l. beaker surrounded by an ice-salt bath , and fitted with a mechanical stirrer and a thermometer, are placed 420 g. (392 ml., 5 moles) of thiophene and 200 ml. of concentrated hydrochloric acid. A rapid stream of hydrogen chloride is passed continuously into the mixture with vigorous stirring. When the temperature reaches 0°, 500 ml. of 37% formaldehyde solution is added at a rate that will permit the temperature to remain below 5°. The addition requires about 4 hours. When all the formaldehyde solution has been added, the mixture is extracted with three 500-ml. portions of ether. The ether extracts are combined, washed successively with water and saturated sodium bicarbonate solution, and then dried over anhydrous calcium chloride. The solvent is removed by distillation, and the product is distilled under reduced pressure through a 50-cm. fractionating column. The product boiling at 73–75°/17 mm. is collected. The yield is 257–267 g. (40–41%) of a colorless oily liquid.
I synthesized 2-chloromethylthiophene from thiophene, concentrated hydrochloric acid, and formaldehyde.
by CognitiveFuel January 21, 2024
Get the 2-chloromethylthiophenemug. Vitamin P is code for Prolintane. Prolintane is a stimulant of norepinephrine-dopamine reuptake inhibitors developed in the 1950s. This is a pretty awesome stimulant that is sometimes used by overachievers and nootropic freaks. The dose range is 20mg to 40mg and the duration is 7 hours to over 12 hours. It is a mild stimulant with a very good safety profile. It works best if cycled(some time on Vitamin P, some time off Vitamin P). It has recently gained popularity among college students and professionals. The one side effect is that you may become a chatterbox while on Vitamin P. Prolintane is a nootropic with a better safety profile than propylhexedrine, cyclopentamine and caffeine. Prolintane is often referred to as Vitamin P and can go for as much as $20 dollars per 40mg dose. Doses of 40mg or more or continual use without breaks makes you hyper. Vitamin P makes you courageous, but you may seem to bold and occasionally act like a talkative nutbar. Your mind would literally feel like it's been overclocked. Vitamin P has no withdrawal effects and seems like a hybrid of caffeine
and NZT-jr.
and NZT-jr.
College student: Dude! I got so much work to do and all these classes and homework.
College student 2: I've got some Vitamin P!
College student: How much? I really have so much work, I'll need a super brain for it all.
College student 2: I'll give you 100mg for $20.
College student : Cool!
3 weeks later!
College student: I'm amazed by the increase in organization skills, better memory and focus, more energy, and lack of withdrawal simptoms. It's best in the morning though. I feel great! This is like the precious NZT and it's all mine. ALL MINE! Must stock up on prolintane, hydrafinil, phenylpiracetam hydrazide, and all cognitive enhancing substances.
College student 2: I've think you've gone mad with power.
College student: Of course I did! Have you ever tried going mad without power?! It sucks! Nobody listens to you.
-10 years later-
College student 2: You're a professional?
College student: Sure! I owe it all to healthy living, going gluten free because I'm gluten intolerant, plenty of excersice, and good old fashioned prolintane. PROLINTANE!
College student 2: Stop biohacking!
College student: NEVER! As long as I cycle my nootropics, stay healthy, and take supplements and breaks, I'll becoome a galactic overlord.
College student 2: I've got some Vitamin P!
College student: How much? I really have so much work, I'll need a super brain for it all.
College student 2: I'll give you 100mg for $20.
College student : Cool!
3 weeks later!
College student: I'm amazed by the increase in organization skills, better memory and focus, more energy, and lack of withdrawal simptoms. It's best in the morning though. I feel great! This is like the precious NZT and it's all mine. ALL MINE! Must stock up on prolintane, hydrafinil, phenylpiracetam hydrazide, and all cognitive enhancing substances.
College student 2: I've think you've gone mad with power.
College student: Of course I did! Have you ever tried going mad without power?! It sucks! Nobody listens to you.
-10 years later-
College student 2: You're a professional?
College student: Sure! I owe it all to healthy living, going gluten free because I'm gluten intolerant, plenty of excersice, and good old fashioned prolintane. PROLINTANE!
College student 2: Stop biohacking!
College student: NEVER! As long as I cycle my nootropics, stay healthy, and take supplements and breaks, I'll becoome a galactic overlord.
by CognitiveFuel December 18, 2014
Get the Vitamin Pmug. PCC is Pyridinium ChloroChromate (Pyridinium chlorochromate). It oxidizes primary alcohols to aldehydes and secondary alcohols to ketones. One has to be careful with the amount of water present in the reaction. If water is present, it can add to the aldehyde to create the hydrate, which could be further oxidized by a second equivalent of PCC if it is present. This is not a concern with ketones because there is no H directly bonded to C
Tony: I oxidized ethanol (100% drinking alcohol, ethyl alcohol) to ethanal (acetaldehyde, the stuff that gives you hangovers) while keeping things dry to prevent over oxidation to ethanoic acid (acetic acid, pure vinegar, final metabolite of ethanol). Then I chloromethylated thiophene to 2-(chloromethyl)thiophene. Then I condensed acetaldehyde with ethylamine to form acetaldehyde ethylimine. Then I formed a grignard reagent of 2-(methylmagnesium chloro)thiophene and reacted them in diethyl ether to form ethiopropamine (EPA). This stimulant could be used for ADHD and ADD. It makes you confident, happy, helps you remember stuff, and keeps you focused. It's weaker than Ritalin, but it's stronger than coffee.
Warning /!\: Research chemicals have not been evaluated for long term effects and is not for human consumption.
CH3CH2OH --PCC--> CH3CHO
Warning /!\: Research chemicals have not been evaluated for long term effects and is not for human consumption.
CH3CH2OH --PCC--> CH3CHO
by CognitiveFuel September 11, 2023
Get the PCCmug. When you are buying drugs from a dealer, you want them to show you the weed, speed, ecstasy, cathinone, Adderall, Ritalin, or Modafinil first. If they don't show you the drugs and the dealer just asks for money first then they're scamming you because they will say "wait here" then disappear and don't have drugs. Product first!
Dealer: Want weed?
Fernando: Sure!
Dealer: Give me $20.
Fernando: Product first!
Dealer: I got the weed. Trust me, bro.
Fernando: Pulls a gun and shoots fake dealer.
Fernando: Sure!
Dealer: Give me $20.
Fernando: Product first!
Dealer: I got the weed. Trust me, bro.
Fernando: Pulls a gun and shoots fake dealer.
by CognitiveFuel December 31, 2022
Get the Product firstmug. A lunar eclipse is when the Earth's shadow blocks the full moon, making it look red and dark.
A lunar eclipse is also when you're mooning (exposing your butt to) someone in broad daylight and a plane blocks the sun for a few seconds, casting a shadow on the moon (butt).
A lunar eclipse is also when you're mooning (exposing your butt to) someone in broad daylight and a plane blocks the sun for a few seconds, casting a shadow on the moon (butt).
It was nighttime and all the people came to watch the lunar eclipse (Earth's shadow blocking the moon for a while).
Tom was mooning people and then a plane passed by to cast a shadow. It was a lunar eclipse (shadow blocking butt).
Tom was mooning people and then a plane passed by to cast a shadow. It was a lunar eclipse (shadow blocking butt).
by CognitiveFuel September 2, 2023
Get the Lunar Eclipsemug. 4,4'-Difluorobenzophenone (4,4-Difluorobenzophenone; 4 4-Difluorobenzophenone; 4 4'-Difluorobenzophenone) is an intermediate in the synthesis of the polymer PEEK and is also used in the synthesis of Flodafinil (Flmodafinil, Difluoromodafinil), Fladrafinil (Difluoroadrafinil) and Modafiendz (N-Methyl-Flodafinil, N-Methyl-Flmodafinil).
Tony: I synthesized Flodafinil (Flmodafinil) by using 4,4'-Difluorobenzophenone and sodium borohydride in ethanol, then converting the 4,4'-(Difluorophenyl)methanol to 4,4'-(Difluorophenyl)methyl bromide using Hydrobromic acid and Zinc chloride catalyst. Then reacting it with sodium thioglycolate. Then a few more steps and I got Flodafinil.
by CognitiveFuel September 11, 2023
Get the 4,4'-Difluorobenzophenonemug. The much cooler way of spelling Valium. It's a pill to help you relax. It is a benzo (benzodiazepine). The dose is 2 to 10mg taken 2 to 4 times a day. For added relaxation, you can combine it with Kratom. Vallium can become addictive. If you combine it with alcohol (ethanol, deathanol), you will black out.
Alex: I took 5mg of Vallium and now I'm relaxed.
Steve: Don't you mean Valium?
Alex: It's Vallium dumbass! No one says Valium anymore! Are you a Pasbt Blue Ribbon drinking hipster who uses apple products with no headphone jack!!!?
Steve: *hides apple phone and Pabst Blue Ribbon!
Steve: No?
Steve: Don't you mean Valium?
Alex: It's Vallium dumbass! No one says Valium anymore! Are you a Pasbt Blue Ribbon drinking hipster who uses apple products with no headphone jack!!!?
Steve: *hides apple phone and Pabst Blue Ribbon!
Steve: No?
by CognitiveFuel December 7, 2022
Get the Valliummug.