yoyoy

It's a plain statement. It's particularly used when someone does something weird.

Your friend: I managed to do poo-poo while standing up
You: yoyoy.

by Nature11 November 13, 2020

Yoyoy

A cry of despair. Acronym slang for "why oh why oh why?".

Man, yoyoy did the kid have to upchuck on my interview suit?

by M. Souris April 30, 2005

yoyoi

A hidden way of saying you enjoy the act of pegging a yo-yo collector

Lucy: "Okay yoyoi."
Everyone else, collectively: "Shut up."

by Esmedidthis November 22, 2021