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A sarcastic remark to an unamusing statment, comment, joke, or question. Most people when saying "Yo Sick" tend to point both arms in the direction of the person who has made the idiotic comment. It is also custom to add the person's name at the end of the "Yo Sick"
Yo Sick: Adjective describing someone unamusing

Person 1: Stupid comment nobody cares about
Person 2: Yooo sick

Eckel: Guys the broncons are going to win the superbowl and the Uconn huskies are going to win the NCAA national championship
Everyone in the General Area: Yoooo Sick Eckel

Austin Allen: Whats up Davey Burgers
Eckel: Yooo sick Don
Yo Sick by Dan Archer July 6, 2008
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Super Sick Yo 

A phrase popularized by a bunch of brain-dead 8th graders in a LasVegas middle school. It's usually said prior to an un-funny joke.
Irvin: I just found $5!
Yumi: That's pretty super sick yo!
Super Sick Yo by EmersonH September 20, 2009
Related Words

Maeson Yosick 

Don't be a Maeson Yosick.
Maeson Yosick by Jo Weimer April 8, 2022

Breadhead 

Someone who is addicted to obtaining money and building wealth. A money addict and fanatic. Breadheads often work more than one full-time job, and some even participate in illicit activities to "obtain the bread".
A breadhead is like a crackhead, but for money instead of crack.
Breadhead by 🅱️ U S 3 4 8 March 30, 2022

Stink lines

As seen in illustrations or cartoons: Wavy, vertical lines rising above a person, place or thing. Denotes a foul odor.
"You didn't put enough stink lines on your picture of the teacher."
Stink lines by Athene Airheart March 14, 2004

schmegegge 

Yiddish slang word meaning bullshit, baloney, hogwash, nonsense, crock of shit or hot air.
I don't buy the schmegegge about Morty sleeping with Moira.
His version of the story was pure schmegegge.
The whole schmegegge was made up to get Liz a little bit of attention.
schmegegge by budsbabe February 1, 2008

eye bleach 

Looking or experiencing something nice after witnessing something horrid like a disgusting gif or a disturbing video. Typically used as eye bleach are nice images of whatever makes the disturbed person happy.
"Bleach my eyes! Why is that woman's face ripped off!?"
*Looks up images of puppies and kittens.*
"That's good eye bleach."
eye bleach by Rini2012 November 29, 2016